Addition of Zoledronate to Chemotherapy in Patients with Osteosarcoma Treated with Limb-Sparing Surgery: A Phase III Clinical Trial

BACKGROUND: Zoledronate has anti-bone resorption activity and is reported to reduce skeletal-related events. The objective of this study was to test the hypothesis that addition of zoledronate in chemotherapy is safe and effective in osteosarcoma. MATERIAL/METHODS: A total of 798 patients, age 25 ye...

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Detalles Bibliográficos
Autores principales: Li, Shenglong, Chen, Peng, Pei, Yi, Zheng, Ke, Wang, Wei, Qiu, Enduo, Zhang, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397617/
https://www.ncbi.nlm.nih.gov/pubmed/30796194
http://dx.doi.org/10.12659/MSM.913236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397617/
https://www.ncbi.nlm.nih.gov/pubmed/30796194
http://dx.doi.org/10.12659/MSM.913236

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