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Identification of a novel potassium channel (GiK) as a potential drug target in Giardia lamblia: Computational descriptions of binding sites

BACKGROUND: The protozoan Giardia lamblia is the causal agent of giardiasis, one of the main diarrheal infections worldwide. Drug resistance to common antigiardial agents and incidence of treatment failures have increased in recent years. Therefore, the search for new molecular targets for drugs aga...

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Detalles Bibliográficos
Autores principales: Palomo-Ligas, Lissethe, Gutiérrez-Gutiérrez, Filiberto, Ochoa-Maganda, Verónica Yadira, Cortés-Zárate, Rafael, Charles-Niño, Claudia Lisette, Castillo-Romero, Araceli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397635/
https://www.ncbi.nlm.nih.gov/pubmed/30834181
http://dx.doi.org/10.7717/peerj.6430