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The role of DNA methylation in epigenetics of aging

Recent research suggests that epigenetics, especially DNA methylation, plays a mechanistic role in aging. Epigenetic clocks, which measure changes in a few hundred specific CpG sites, can accurately predict chronological age in a variety of species, including humans. These clocks are currently the b...

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Detalles Bibliográficos
Autores principales: Unnikrishnan, Archana, Freeman, Willard M., Jackson, Jordan, Wren, Jonathan D., Porter, Hunter, Richardson, Arlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397707/
https://www.ncbi.nlm.nih.gov/pubmed/30419258
http://dx.doi.org/10.1016/j.pharmthera.2018.11.001