Cargando…

The role of DNA methylation in epigenetics of aging

Recent research suggests that epigenetics, especially DNA methylation, plays a mechanistic role in aging. Epigenetic clocks, which measure changes in a few hundred specific CpG sites, can accurately predict chronological age in a variety of species, including humans. These clocks are currently the b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Unnikrishnan, Archana, Freeman, Willard M., Jackson, Jordan, Wren, Jonathan D., Porter, Hunter, Richardson, Arlan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397707/ https://www.ncbi.nlm.nih.gov/pubmed/30419258 http://dx.doi.org/10.1016/j.pharmthera.2018.11.001

Ejemplares similares

Role of DNA methylation in the dietary restriction mediated cellular memory
por: Unnikrishnan, Archana, et al.
Publicado: (2017)

Sexually divergent DNA methylation patterns with hippocampal aging
por: Masser, Dustin R., et al.
Publicado: (2017)

Litter expansion alters metabolic homeostasis in a sex specific manner
por: Kurup, Kavitha, et al.
Publicado: (2021)

Necroptosis increases with age and is reduced by dietary restriction
por: Deepa, Sathyaseelan S., et al.
Publicado: (2018)

Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice
por: Hadad, Niran, et al.
Publicado: (2016)

Calorie restriction prevents age-related changes in the intestinal microbiota
por: Kurup, Kavitha, et al.
Publicado: (2021)

Many chronological aging clocks can be found throughout the epigenome: Implications for quantifying biological aging
por: Porter, Hunter L., et al.
Publicado: (2021)

A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1(−/)(−) mice is correlated to increased cellular senescence
por: Zhang, Yiqiang, et al.
Publicado: (2016)

Characterization of novel mouse models to study the role of necroptosis in aging and age-related diseases
por: Selvarani, Ramasamy, et al.
Publicado: (2023)

Is Rapamycin a Dietary Restriction Mimetic?
por: Unnikrishnan, Archana, et al.
Publicado: (2020)

Caloric restriction and genomic stability
por: Heydari, Ahmad R., et al.
Publicado: (2007)

Epigenetic Clock: DNA Methylation in Aging
por: Jiang, Shuang, et al.
Publicado: (2020)

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia
por: Chucair-Elliott, Ana J., et al.
Publicado: (2020)

Association of facial ageing with DNA methylation and epigenetic age predictions
por: Marioni, Riccardo E., et al.
Publicado: (2018)

Infant's DNA Methylation Age at Birth and Epigenetic Aging Accelerators
por: Javed, Ruheena, et al.
Publicado: (2016)

Epigenetics of Male Infertility: The Role of DNA Methylation
por: Rotondo, John Charles, et al.
Publicado: (2021)

Epigenetics and stroke: role of DNA methylation and effect of aging on blood–brain barrier recovery
por: Phillips, Chelsea M., et al.
Publicado: (2023)

An epigenetic role for noncoding RNAs and intragenic DNA methylation
por: Flanagan, James M, et al.
Publicado: (2007)

Effects of transgenic methionine sulfoxide reductase A (MsrA) expression on lifespan and age-dependent changes in metabolic function in mice
por: Salmon, Adam B., et al.
Publicado: (2016)

Epigenetics of Delirium and Aging: Potential Role of DNA Methylation Change on Cytokine Genes in Glia and Blood Along With Aging
por: Shinozaki, Gen, et al.
Publicado: (2018)

Epigenetics and stroke: role of DNA methylation and effect of aging on blood-brain barrier recovery
por: Phillips, Chelsea, et al.
Publicado: (2023)

Early-life DNA methylation profiles are indicative of age-related transcriptome changes
por: Hadad, Niran, et al.
Publicado: (2019)

Epigenetics and the overhealing wound: the role of DNA methylation in fibrosis
por: Neary, Roisin, et al.
Publicado: (2015)

DNA methylation variations and epigenetic aging in telomere biology disorders
por: Carlund, Olivia, et al.
Publicado: (2023)

Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity
por: Schachtschneider, Kyle M., et al.
Publicado: (2021)

The Key Role of DNA Methylation and Histone Acetylation in Epigenetics of Atherosclerosis
por: Lee, Han-Teo, et al.
Publicado: (2020)

Epigenetic Changes in Asthma: Role of DNA CpG Methylation
por: Bae, Da-Jeong, et al.
Publicado: (2020)

Targeted DNA Methylation Analysis by Next-generation Sequencing
por: Masser, Dustin R., et al.
Publicado: (2015)

Effect of rapamycin on aging and age-related diseases—past and future
por: Selvarani, Ramasamy, et al.
Publicado: (2020)

Epigenetic regulation of hematopoiesis by DNA methylation
por: Gore, Aniket V, et al.
Publicado: (2016)

DNA methylation age at birth and childhood: performance of epigenetic clocks and characteristics associated with epigenetic age acceleration in the Project Viva cohort
por: Bozack, Anne K., et al.
Publicado: (2023)

Epigenetic DNA Methylation Linked to Social Dominance
por: Lenkov, Kapa, et al.
Publicado: (2015)

Accelerated epigenetic aging and DNA methylation alterations in Berardinelli–Seip congenital lipodystrophy
por: Qannan, Abeer, et al.
Publicado: (2023)

Epigenetics in psychiatry: Beyond DNA methylation
por: Kouter, Katarina, et al.
Publicado: (2023)

Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci
por: Sugrue, Victoria J, et al.
Publicado: (2021)

Role of nerve–muscle interactions and reactive oxygen species in regulation of muscle proteostasis with ageing
por: Vasilaki, Aphrodite, et al.
Publicado: (2017)

Role of methionine on epigenetic modification of DNA methylation and gene expression in animals
por: Zhang, Naifeng
Publicado: (2018)

Epigenetic Studies of Chinese Herbal Medicine: Pleiotropic Role of DNA Methylation
por: Guo, Wenqian, et al.
Publicado: (2021)

Relationship of tobacco smoking and smoking-related DNA methylation with epigenetic age acceleration
por: Gao, Xu, et al.
Publicado: (2016)

The influences of DNA methylation and epigenetic clocks, on metabolic disease, in middle-aged Koreans
por: Lee, Ho-Sun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vbr6eie82odc30dvih0gq0po6k