Immunohistochemical Characterization of Procaspase-3 Overexpression as a Druggable Target With PAC-1, a Procaspase-3 Activator, in Canine and Human Brain Cancers

Gliomas and meningiomas are the most common brain neoplasms affecting both humans and canines, and identifying druggable targets conserved across multiple brain cancer histologies and comparative species could broadly improve treatment outcomes. While satisfactory cure rates for low grade, non-invas...

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Detalles Bibliográficos
Autores principales: Schlein, Lisa J., Fadl-Alla, Bahaa, Pondenis, Holly C., Lezmi, Stéphane, Eberhart, Charles G., LeBlanc, Amy K., Dickinson, Peter J., Hergenrother, Paul J., Fan, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397847/
https://www.ncbi.nlm.nih.gov/pubmed/30859090
http://dx.doi.org/10.3389/fonc.2019.00096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397847/
https://www.ncbi.nlm.nih.gov/pubmed/30859090
http://dx.doi.org/10.3389/fonc.2019.00096

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