A Computational Model of Loss of Dopaminergic Cells in Parkinson's Disease Due to Glutamate-Induced Excitotoxicity

Parkinson's disease (PD) is a neurodegenerative disease associated with progressive and inexorable loss of dopaminergic cells in Substantia Nigra pars compacta (SNc). Although many mechanisms have been suggested, a decisive root cause of this cell loss is unknown. A couple of the proposed mecha...

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Detalles Bibliográficos
Autores principales: Muddapu, Vignayanandam Ravindernath, Mandali, Alekhya, Chakravarthy, V. Srinivasa, Ramaswamy, Srikanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397878/
https://www.ncbi.nlm.nih.gov/pubmed/30858799
http://dx.doi.org/10.3389/fncir.2019.00011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397878/
https://www.ncbi.nlm.nih.gov/pubmed/30858799
http://dx.doi.org/10.3389/fncir.2019.00011

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