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Squalene epoxidase promotes the proliferation and metastasis of lung squamous cell carcinoma cells though extracellular signal‐regulated kinase signaling

BACKGROUND: The biological function of squalene epoxidase (SQLE), an important rate‐limiting enzyme in downstream cholesterol synthesis, is to convert squalene to 2‐3 oxacin squalene. The expression of SQLE in lung cancer is abnormal. We conducted this study to investigate the effect of SQLE express...

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Detalles Bibliográficos
Autores principales: Ge, Hong, Zhao, Yamei, Shi, Xinyan, Tan, Zhen, Chi, Xiaorui, He, Man, Jiang, Guohui, Ji, Lixia, Li, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397918/
https://www.ncbi.nlm.nih.gov/pubmed/30734525
http://dx.doi.org/10.1111/1759-7714.12944