The Specific Inhibition of SOD1 Selectively Promotes Apoptosis of Cancer Cells via Regulation of the ROS Signaling Network

Multiple signaling pathways including ERK, PI3K-Akt, and NF-κB, which are essential for onset and development of cancer, can be activated by intracellularly sustained high levels of H(2)O(2) provided by elevated activity and expression of copper/zinc superoxide dismutase (SOD1) that catalyzes the di...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Chen, Yuanyuan, Zhao, Jidong, Shi, Jiayuan, Wang, Mingfang, Qiu, Shuang, Hu, Yinghui, Xu, Yulin, Cui, Yanfang, Liu, Chunrong, Liu, Changlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398008/
https://www.ncbi.nlm.nih.gov/pubmed/30911355
http://dx.doi.org/10.1155/2019/9706792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398008/
https://www.ncbi.nlm.nih.gov/pubmed/30911355
http://dx.doi.org/10.1155/2019/9706792

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