Cargando…

The Specific Inhibition of SOD1 Selectively Promotes Apoptosis of Cancer Cells via Regulation of the ROS Signaling Network

Multiple signaling pathways including ERK, PI3K-Akt, and NF-κB, which are essential for onset and development of cancer, can be activated by intracellularly sustained high levels of H(2)O(2) provided by elevated activity and expression of copper/zinc superoxide dismutase (SOD1) that catalyzes the di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xiang, Chen, Yuanyuan, Zhao, Jidong, Shi, Jiayuan, Wang, Mingfang, Qiu, Shuang, Hu, Yinghui, Xu, Yulin, Cui, Yanfang, Liu, Chunrong, Liu, Changlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398008/ https://www.ncbi.nlm.nih.gov/pubmed/30911355 http://dx.doi.org/10.1155/2019/9706792

Ejemplares similares

SAXS Examinations of the Redox-Dependent Formation of a DNA-SOD1 Complex
por: Wang, Huiling, et al.
Publicado: (2022)

The rational design of specific SOD1 inhibitors via copper coordination and their application in ROS signaling research
por: Dong, Xiongwei, et al.
Publicado: (2016)

A new function of copper zinc superoxide dismutase: as a regulatory DNA-binding protein in gene expression in response to intracellular hydrogen peroxide
por: Li, Xiang, et al.
Publicado: (2019)

Exogenous C(8)-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells
por: Chang, Yuli C., et al.
Publicado: (2018)

Race and sex differences in ROS production and SOD activity in HUVECs
por: Mascone, Sara E., et al.
Publicado: (2023)

PPARγ/SOD2 Protects Against Mitochondrial ROS-Dependent Apoptosis via Inhibiting ATG4D-Mediated Mitophagy to Promote Pancreatic Cancer Proliferation
por: Nie, Shuang, et al.
Publicado: (2022)

A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease
por: Celotto, Alicia M, et al.
Publicado: (2012)

Mechanistic study of mtROS-JNK-SOD2 signaling in bupivacaine-induced neuron oxidative stress
por: Liu, Zhongjie, et al.
Publicado: (2020)

Dihydromyricetin functions as a tumor suppressor in hepatoblastoma by regulating SOD1/ROS pathway
por: Guo, Tong, et al.
Publicado: (2023)

SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin
por: Pi, Huifeng, et al.
Publicado: (2015)

Making ROS for apoptosis
por: Tuma, Rabiya S.
Publicado: (2005)

Excessive mitochondrial fragmentation triggered by erlotinib promotes pancreatic cancer PANC-1 cell apoptosis via activating the mROS-HtrA2/Omi pathways
por: Wan, Jun, et al.
Publicado: (2018)

Alterations in Concentration/Activity of Superoxide Dismutases in Context of Obesity and Selected Single Nucleotide Polymorphisms in Genes: SOD1, SOD2, SOD3
por: Lewandowski, Łukasz, et al.
Publicado: (2020)

Superoxide Dismutases (SODs) and SOD Mimetics
por: Borgstahl, Gloria E. O., et al.
Publicado: (2018)

MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signaling in cancer
por: Hart, Peter C., et al.
Publicado: (2015)

Harnessing ROS-Induced Oxidative Stress for Halting Colorectal Cancer via Thiazolidinedione-Based SOD Inhibitors
por: Abd Al Moaty, Mohamed Nabil, et al.
Publicado: (2022)

Retraction Note to: Excessive mitochondrial fragmentation triggered by erlotinib promotes pancreatic cancer PANC‑1 cell apoptosis via activating the mROS‑HtrA2/Omi pathways
por: Wan, Jun, et al.
Publicado: (2019)

Fucosylated oligosaccharide Lacto-N-fucopentaose I ameliorates enterovirus 71 infection by inhibiting apoptosis
por: Gao, Xiaoxiang, et al.
Publicado: (2022)

SOD3 and eNOS genotypes are associated with SOD activity and NO(x)
por: DONG, XIAOLONG, et al.
Publicado: (2014)

Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS
por: Shang, Yinghui, et al.
Publicado: (2021)

Nitric oxide inhibits endothelial cell apoptosis by inhibiting cysteine‐dependent SOD1 monomerization
por: Peng, Hanlin, et al.
Publicado: (2022)

Identification of Human Monoclonal Antibodies Specific for Human SOD1 Recognizing Distinct Epitopes and Forms of SOD1
por: Broering, Teresa J., et al.
Publicado: (2013)

Heterozygous SOD2 deletion deteriorated chronic intermittent hypoxia-induced lung inflammation and vascular remodeling through mtROS-NLRP3 signaling pathway
por: Song, Jie-qiong, et al.
Publicado: (2020)

Nimbolide Induces ROS-Regulated Apoptosis and Inhibits Cell Migration in Osteosarcoma
por: Liu, Ju-Fang, et al.
Publicado: (2015)

Xanthohumol Induces ROS through NADPH Oxidase, Causes Cell Cycle Arrest and Apoptosis
por: Wang, Chun-Ming, et al.
Publicado: (2021)

Dioscin Induces Gallbladder Cancer Apoptosis by Inhibiting ROS-Mediated PI3K/AKT Signalling
por: Song, Xiaoling, et al.
Publicado: (2017)

Acacetin Induces Apoptosis in Human Osteosarcoma Cells by Modulation of ROS/JNK Activation
por: Wang, Shubin, et al.
Publicado: (2020)

JS-K promotes apoptosis by inducing ROS production in human prostate cancer cells
por: Qiu, Mingning, et al.
Publicado: (2017)

Shikonin induces ROS-based mitochondria-mediated apoptosis in colon cancer
por: Liang, Wenquan, et al.
Publicado: (2017)

Genistein inhibits lung cancer cell stem-like characteristics by modulating MnSOD and FoxM1 expression
por: Fu, Zhimin, et al.
Publicado: (2020)

Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells
por: Liu, Ting, et al.
Publicado: (2015)

Codonopsis lanceolata attenuates allergic lung inflammation by inhibiting Th2 cell activation and augmenting mitochondrial ROS dismutase (SOD2) expression
por: Seo, Yun-Soo, et al.
Publicado: (2019)

Superoxide Dismutase Gene (SOD1, SOD2, and SOD3) Polymorphisms and Antituberculosis Drug-induced Hepatitis
por: Kim, Sang-Hoon, et al.
Publicado: (2015)

Sesamin Protects the Femoral Head From Osteonecrosis by Inhibiting ROS-Induced Osteoblast Apoptosis in Rat Model
por: Deng, Shuang, et al.
Publicado: (2018)

Matrine Exerts Hepatotoxic Effects via the ROS-Dependent Mitochondrial Apoptosis Pathway and Inhibition of Nrf2-Mediated Antioxidant Response
por: You, Longtai, et al.
Publicado: (2019)

Modulation of MnSOD and FoxM1 Is Involved in Invasion and EMT Suppression by Isovitexin in Hepatocellular Carcinoma Cells
por: Qiu, Yebei, et al.
Publicado: (2020)

Maresin 1 Alleviates Diabetic Kidney Disease via LGR6-Mediated cAMP-SOD2-ROS Pathway
por: Li, Xinyue, et al.
Publicado: (2022)

Hypertrophic Preconditioning Attenuates Myocardial Ischaemia‐Reperfusion Injury by Modulating SIRT3‐SOD2‐mROS‐Dependent Autophagy
por: Ma, Lei‐Lei, et al.
Publicado: (2021)

ROS Accumulation by PEITC Selectively Kills Ovarian Cancer Cells via UPR-Mediated Apoptosis
por: Hong, Yoon-Hee, et al.
Publicado: (2015)

Cryptotanshinone induces ROS-mediated apoptosis in human gastric cancer cells
por: Liu, Chang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_c9neq7atdrk25l628lcb7f4to8