Evaluation of dextromethorphan with select antidepressant therapy for the treatment of depression in the acute care psychiatric setting

INTRODUCTION: Dextromethorphan (DXM), an N-methyl-D-aspartate receptor antagonist, may have ketamine-like antidepressant effects. Dextromethorphan is extensively metabolized via cytochrome P450 (CYP) 2D6, and its half-life in extensive metabolizers is 2 to 4 hours. The purpose of this study was to e...

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Detalles Bibliográficos
Autores principales: Nofziger, Jill L., Paxos, Chris, Emshoff, Jessica, Mullen, Chanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: College of Psychiatric & Neurologic Pharmacists 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398352/
https://www.ncbi.nlm.nih.gov/pubmed/30842914
http://dx.doi.org/10.9740/mhc.2019.03.076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398352/
https://www.ncbi.nlm.nih.gov/pubmed/30842914
http://dx.doi.org/10.9740/mhc.2019.03.076

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