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Evaluation of dextromethorphan with select antidepressant therapy for the treatment of depression in the acute care psychiatric setting
INTRODUCTION: Dextromethorphan (DXM), an N-methyl-D-aspartate receptor antagonist, may have ketamine-like antidepressant effects. Dextromethorphan is extensively metabolized via cytochrome P450 (CYP) 2D6, and its half-life in extensive metabolizers is 2 to 4 hours. The purpose of this study was to e...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
College of Psychiatric & Neurologic Pharmacists
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398352/ https://www.ncbi.nlm.nih.gov/pubmed/30842914 http://dx.doi.org/10.9740/mhc.2019.03.076 |