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The structure of INI1/hSNF5 RPT1 and its interactions with the c‐MYC:MAX heterodimer provide insights into the interplay between MYC and the SWI/SNF chromatin remodeling complex

c‐MYC and the SWI/SNF chromatin remodeling complex act as master regulators of transcription, and play a key role in human cancer. Although they are known to interact, the molecular details of their interaction are lacking. We have determined the structure of the RPT1 region of the INI1/hSNF5/BAF47/...

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Detalles Bibliográficos
Autores principales: Sammak, Susan, Allen, Mark D., Hamdani, Najoua, Bycroft, Mark, Zinzalla, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398391/
https://www.ncbi.nlm.nih.gov/pubmed/30222246
http://dx.doi.org/10.1111/febs.14660