Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes

Liver development involves dramatic gene expression changes mediated by transcriptional and post-transcriptional control. Here, we show that the Cnot deadenylase complex plays a crucial role in liver functional maturation. The Cnot3 gene encodes an essential subunit of the Cnot complex. Mice lacking...

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Detalles Bibliográficos
Autores principales: Suzuki, Toru, Kikuguchi, Chisato, Nishijima, Saori, Nagashima, Takeshi, Takahashi, Akinori, Okada, Mariko, Yamamoto, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398447/
https://www.ncbi.nlm.nih.gov/pubmed/30733279
http://dx.doi.org/10.1242/dev.168146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398447/
https://www.ncbi.nlm.nih.gov/pubmed/30733279
http://dx.doi.org/10.1242/dev.168146

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