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The Forkhead box F1 transcription factor inhibits collagen deposition and accumulation of myofibroblasts during liver fibrosis

Hepatic fibrosis is the common end stage to a variety of chronic liver injuries and is characterized by an excessive deposition of extracellular matrix (ECM), which disrupts the liver architecture and impairs liver function. The fibrous lesions are produced by myofibroblasts, which differentiate fro...

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Detalles Bibliográficos
Autores principales: Flood, Hannah M., Bolte, Craig, Dasgupta, Nupur, Sharma, Akanksha, Zhang, Yufang, Gandhi, Chandrashekhar R., Kalin, Tanya V., Kalinichenko, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398469/
https://www.ncbi.nlm.nih.gov/pubmed/30670377
http://dx.doi.org/10.1242/bio.039800