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Regulated reconstitution of spindle checkpoint arrest and silencing through chemically induced dimerisation in vivo

Chemically induced dimerisation (CID) uses small molecules to control specific protein–protein interactions. We employed CID dependent on the plant hormone abscisic acid (ABA) to reconstitute spindle checkpoint signalling in fission yeast. The spindle checkpoint signal usually originates at unattach...

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Detalles Bibliográficos
Autores principales: Amin, Priya, Soper Ní Chafraidh, Sadhbh, Leontiou, Ioanna, Hardwick, Kevin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398473/
https://www.ncbi.nlm.nih.gov/pubmed/30237224
http://dx.doi.org/10.1242/jcs.219766