VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation

Members of the VPS13 family are associated with various human diseases. In particular, the loss of function of VPS13A leads to chorea-acanthocytosis (ChAc), a rare neurodegenerative disease without available curative treatments. Autophagy has been considered a promising therapeutic target because th...

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Detalles Bibliográficos
Autores principales: Muñoz-Braceras, Sandra, Tornero-Écija, Alba R., Vincent, Olivier, Escalante, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398486/
https://www.ncbi.nlm.nih.gov/pubmed/30709847
http://dx.doi.org/10.1242/dmm.036681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398486/
https://www.ncbi.nlm.nih.gov/pubmed/30709847
http://dx.doi.org/10.1242/dmm.036681

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