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A double-hit pre-eclampsia model results in sex-specific growth restriction patterns

Pre-eclampsia is a multifactorial pregnancy-associated disorder characterized by angiogenic dysbalance and systemic inflammation; however, animal models that combine these two pathophysiological conditions are missing. Here, we introduce a novel double-hit pre-eclampsia mouse model that mimics the c...

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Detalles Bibliográficos
Autores principales: Stojanovska, Violeta, Dijkstra, Dorieke J., Vogtmann, Rebekka, Gellhaus, Alexandra, Scherjon, Sicco A., Plösch, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398487/
https://www.ncbi.nlm.nih.gov/pubmed/30683649
http://dx.doi.org/10.1242/dmm.035980