A yeast-based screening assay identifies repurposed drugs that suppress mitochondrial fusion and mtDNA maintenance defects

Mitochondria continually move, fuse and divide, and these dynamics are essential for the proper function of the organelles. Indeed, the dynamic balance of fusion and fission of mitochondria determines their morphology and allows their immediate adaptation to energetic needs as well as preserving the...

Descripción completa

Detalles Bibliográficos
Autores principales: Delerue, Thomas, Tribouillard-Tanvier, Déborah, Daloyau, Marlène, Khosrobakhsh, Farnoosh, Emorine, Laurent Jean, Friocourt, Gaëlle, Belenguer, Pascale, Blondel, Marc, Arnauné-Pelloquin, Laetitia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398489/
https://www.ncbi.nlm.nih.gov/pubmed/30658998
http://dx.doi.org/10.1242/dmm.036558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398489/
https://www.ncbi.nlm.nih.gov/pubmed/30658998
http://dx.doi.org/10.1242/dmm.036558

Ejemplares similares