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Differential regulation of the unfolded protein response in outbred deer mice and susceptibility to metabolic disease
Endoplasmic reticulum (ER) stress has been causatively linked to the onset of various pathologies. However, whether and how inherent variations in the resulting unfolded protein response (UPR) affect predisposition to ER-stress-associated metabolic conditions remains to be established. By using gene...
Autores principales: | Havighorst, Amanda, Zhang, Youwen, Farmaki, Elena, Kaza, Vimala, Chatzistamou, Ioulia, Kiaris, Hippokratis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398494/ https://www.ncbi.nlm.nih.gov/pubmed/30733237 http://dx.doi.org/10.1242/dmm.037242 |
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