Liver-specific insulin receptor isoform A expression enhances hepatic glucose uptake and ameliorates liver steatosis in a mouse model of diet-induced obesity

Among the main complications associated with obesity are insulin resistance and altered glucose and lipid metabolism within the liver. It has previously been described that insulin receptor isoform A (IRA) favors glucose uptake and glycogen storage in hepatocytes compared with isoform B (IRB), impro...

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Detalles Bibliográficos
Autores principales: Lopez-Pastor, Andrea Raposo, Gomez-Hernandez, Almudena, Diaz-Castroverde, Sabela, Gonzalez-Aseguinolaza, Gloria, Gonzalez-Rodriguez, Agueda, Garcia, Gema, Fernandez, Silvia, Escribano, Oscar, Benito, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398497/
https://www.ncbi.nlm.nih.gov/pubmed/30642871
http://dx.doi.org/10.1242/dmm.036186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398497/
https://www.ncbi.nlm.nih.gov/pubmed/30642871
http://dx.doi.org/10.1242/dmm.036186

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