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Liver-specific insulin receptor isoform A expression enhances hepatic glucose uptake and ameliorates liver steatosis in a mouse model of diet-induced obesity
Among the main complications associated with obesity are insulin resistance and altered glucose and lipid metabolism within the liver. It has previously been described that insulin receptor isoform A (IRA) favors glucose uptake and glycogen storage in hepatocytes compared with isoform B (IRB), impro...
Autores principales: | Lopez-Pastor, Andrea Raposo, Gomez-Hernandez, Almudena, Diaz-Castroverde, Sabela, Gonzalez-Aseguinolaza, Gloria, Gonzalez-Rodriguez, Agueda, Garcia, Gema, Fernandez, Silvia, Escribano, Oscar, Benito, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398497/ https://www.ncbi.nlm.nih.gov/pubmed/30642871 http://dx.doi.org/10.1242/dmm.036186 |
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