Early detection of pre-malignant lesions in a KRAS(G12D)-driven mouse lung cancer model by monitoring circulating free DNA

Lung cancer is the leading cause of cancer-related death. Two-thirds of cases are diagnosed at an advanced stage that is refractory to curative treatment. Therefore, strategies for the early detection of lung cancer are urgently sought. Total circulating free DNA (cfDNA) and tumour-derived circulati...

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Detalles Bibliográficos
Autores principales: Rakhit, Callum P., Trigg, Ricky M., Le Quesne, John, Kelly, Michael, Shaw, Jacqueline A., Pritchard, Catrin, Martins, L. Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398498/
https://www.ncbi.nlm.nih.gov/pubmed/30760495
http://dx.doi.org/10.1242/dmm.036863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398498/
https://www.ncbi.nlm.nih.gov/pubmed/30760495
http://dx.doi.org/10.1242/dmm.036863

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