Leptin induces muscle wasting in a zebrafish kras-driven hepatocellular carcinoma (HCC) model

Cancer cachexia affects up to 80% of patients with advanced solid cancer and leads to excessive muscle wasting. Here, using an inducible zebrafish hepatocellular carcinoma (HCC) model driven by oncogenic kras(G12V), we observed a progressive muscle-wasting phenotype in adult zebrafish, characterized...

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Detalles Bibliográficos
Autores principales: Yang, Qiqi, Yan, Chuan, Wang, Xu, Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398506/
https://www.ncbi.nlm.nih.gov/pubmed/30718259
http://dx.doi.org/10.1242/dmm.038240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398506/
https://www.ncbi.nlm.nih.gov/pubmed/30718259
http://dx.doi.org/10.1242/dmm.038240

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