Cargando…
Leptin induces muscle wasting in a zebrafish kras-driven hepatocellular carcinoma (HCC) model
Cancer cachexia affects up to 80% of patients with advanced solid cancer and leads to excessive muscle wasting. Here, using an inducible zebrafish hepatocellular carcinoma (HCC) model driven by oncogenic kras(G12V), we observed a progressive muscle-wasting phenotype in adult zebrafish, characterized...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398506/ https://www.ncbi.nlm.nih.gov/pubmed/30718259 http://dx.doi.org/10.1242/dmm.038240 |