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Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity

Reduced growth hormone (GH) signaling has been consistently associated with increased health and lifespan in various mouse models. Here, we assessed GH secretion and its control in relation with human familial longevity. We frequently sampled blood over 24 h in 19 middle‐aged offspring of long‐livin...

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Detalles Bibliográficos
Autores principales: van der Spoel, Evie, Jansen, Steffy W., Akintola, Abimbola A., Ballieux, Bart E., Cobbaert, Christa M., Slagboom, P. Eline, Blauw, Gerard Jan, Westendorp, Rudi G. J., Pijl, Hanno, Roelfsema, Ferdinand, van Heemst, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398524/
https://www.ncbi.nlm.nih.gov/pubmed/27605408
http://dx.doi.org/10.1111/acel.12519