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Amyloid β‐induced astrogliosis is mediated by β1‐integrin via NADPH oxidase 2 in Alzheimer's disease

Astrogliosis is a hallmark of Alzheimer′s disease (AD) and may constitute a primary pathogenic component of that disorder. Elucidation of signaling cascades inducing astrogliosis should help characterizing the function of astrocytes and identifying novel molecular targets to modulate AD progression....

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Detalles Bibliográficos
Autores principales: Wyssenbach, Ane, Quintela, Tania, Llavero, Francisco, Zugaza, Jose L., Matute, Carlos, Alberdi, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398528/
https://www.ncbi.nlm.nih.gov/pubmed/27709751
http://dx.doi.org/10.1111/acel.12521