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Improved Differential Diagnosis of Alzheimer’s Disease by Integrating ELISA and Mass Spectrometry-Based Cerebrospinal Fluid Biomarkers

BACKGROUND: Alzheimer’s disease (AD) is diagnosed based on a clinical evaluation as well as analyses of classical biomarkers: Aβ(42), total tau (t-tau), and phosphorylated tau (p-tau) in cerebrospinal fluid (CSF). Although the sensitivities and specificities of the classical biomarkers are fairly go...

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Detalles Bibliográficos
Autores principales: Khoonsari, Payam Emami, Shevchenko, Ganna, Herman, Stephanie, Remnestål, Julia, Giedraitis, Vilmantas, Brundin, RoseMarie, Degerman Gunnarsson, Malin, Kilander, Lena, Zetterberg, Henrik, Nilsson, Peter, Lannfelt, Lars, Ingelsson, Martin, Kultima, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398544/
https://www.ncbi.nlm.nih.gov/pubmed/30614806
http://dx.doi.org/10.3233/JAD-180855