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MicroRNA-539 inhibits the progression of Wilms’ Tumor through downregulation of JAG1 and Notch1/3

BACKGROUND: Previous studies demonstrated that miR-539 play an important role in the carcinogenesis of some cancers. The aim of the present study was to determine the role of miR-539 in the pathogenesis of Wilms’ Tumor (WT). METHODS: The expression level of miR-539 was measured by qRT-PCR in 42 WT t...

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Detalles Bibliográficos
Autores principales: Su, Hailong, Wang, Xuebo, Song, Jingjing, Wang, Yongjiao, Zhao, Yingchun, Meng, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398546/
https://www.ncbi.nlm.nih.gov/pubmed/30530967
http://dx.doi.org/10.3233/CBM-181972