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The Amphetamine Induced Rotation Test: A Re-Assessment of Its Use as a Tool to Monitor Motor Impairment and Functional Recovery in Rodent Models of Parkinson’s Disease
Rats and mice with unilateral damage to the nigrostriatal dopamine system—induced by neurotoxins, such as 6-hydroxydopamine, overexpression of α-synuclein, or injections of toxic synuclein protofibrils—are widely used as experimental models to mimic the loss of dopamine neurons seen in Parkinson’s d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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IOS Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398560/ https://www.ncbi.nlm.nih.gov/pubmed/30741691 http://dx.doi.org/10.3233/JPD-181525 |