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HSP90 and Its Novel Co-Chaperones, SGT1 and CHP-1, in Brain of Patients with Parkinson’s Disease and Dementia with Lewy Bodies

BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the presence of inclusions known as Lewy bodies in some brain regions. Lewy bodies consist of α-synuclein and many other proteins including chaperones. OBJECTIVE: To learn more about the role of chaperone complexes...

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Detalles Bibliográficos
Autores principales: Bohush, Anastasiia, Niewiadomska, Grażyna, Weis, Serge, Filipek, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398563/
https://www.ncbi.nlm.nih.gov/pubmed/30741686
http://dx.doi.org/10.3233/JPD-181443