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The ERK and JNK pathways in the regulation of metabolic reprogramming

Most tumor cells reprogram their glucose metabolism as a result of mutations in oncogenes and tumor suppressors, leading to the constitutive activation of signaling pathways involved in cell growth. This metabolic reprogramming, known as aerobic glycolysis or the Warburg effect, allows tumor cells t...

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Detalles Bibliográficos
Autores principales: Papa, Salvatore, Choy, Pui Man, Bubici, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398583/
https://www.ncbi.nlm.nih.gov/pubmed/30487597
http://dx.doi.org/10.1038/s41388-018-0582-8