Cargando…
The ERK and JNK pathways in the regulation of metabolic reprogramming
Most tumor cells reprogram their glucose metabolism as a result of mutations in oncogenes and tumor suppressors, leading to the constitutive activation of signaling pathways involved in cell growth. This metabolic reprogramming, known as aerobic glycolysis or the Warburg effect, allows tumor cells t...
Autores principales: | Papa, Salvatore, Choy, Pui Man, Bubici, Concetta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398583/ https://www.ncbi.nlm.nih.gov/pubmed/30487597 http://dx.doi.org/10.1038/s41388-018-0582-8 |
Ejemplares similares
-
Editorial: The Warburg Effect Regulation Under Siege: the Intertwined Pathways in Health and Disease
por: Bubici, Concetta, et al.
Publicado: (2019) -
Linking apoptosis to cancer metabolism: Another missing piece of JuNK
por: Papa, Salvatore, et al.
Publicado: (2016) -
PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation
por: Iansante, Valeria, et al.
Publicado: (2015) -
High Expression of Glycolytic Genes in Cirrhosis Correlates With the Risk of Developing Liver Cancer
por: Lee, Nathan C. W., et al.
Publicado: (2018) -
ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T‐Cell Metabolism
por: Tan, Xiaosheng, et al.
Publicado: (2023)