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PROFIT, a PROspective, randomised placebo controlled feasibility trial of Faecal mIcrobiota Transplantation in cirrhosis: study protocol for a single-blinded trial

INTRODUCTION: Patients with advanced cirrhosis have enteric bacterial dysbiosis and translocation of bacteria and their products across the gut epithelial barrier. This culminates in systemic inflammation and endotoxaemia, inducing innate immune dysfunction which predisposes to infection, and develo...

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Detalles Bibliográficos
Autores principales: Woodhouse, Charlotte Alexandra, Patel, Vishal C, Goldenberg, Simon, Sanchez-Fueyo, Alberto, China, Louise, O’Brien, Alastair, Flach, Clare, Douiri, Abdel, Shawcross, Debbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398649/
https://www.ncbi.nlm.nih.gov/pubmed/30772848
http://dx.doi.org/10.1136/bmjopen-2018-023518