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Trial summary and protocol for a phase II randomised placebo-controlled double-blinded trial of Interleukin 1 blockade in Acute Severe Colitis: the IASO trial

INTRODUCTION: Acute severe ulcerative colitis (ASUC) is a severe manifestation of ulcerative colitis (UC) that warrants hospitalisation. Despite significant advances in therapeutic options for UC and in the medical management of steroid-refractory ASUC, the initial treatment paradigm has not changed...

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Detalles Bibliográficos
Autores principales: Thomas, Martin Geoffrey, Bayliss, Carrie, Bond, Simon, Dowling, Francis, Galea, James, Jairath, Vipul, Lamb, Christopher, Probert, Christopher, Timperley-Preece, Elizabeth, Watson, Alastair, Whitehead, Lynne, Williams, John G, Parkes, Miles, Kaser, Arthur, Raine, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398753/
https://www.ncbi.nlm.nih.gov/pubmed/30772849
http://dx.doi.org/10.1136/bmjopen-2018-023765