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Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells
Accumulation of mutations in mitochondrial DNA (mtDNA) is thought to be responsible for mitochondrial, and other, diseases and biological phenomena, such as diabetes, cancer, neurodegenerative diseases, and aging. Mouse models may elucidate the relationship between mutations in mtDNA and these abnor...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398856/ https://www.ncbi.nlm.nih.gov/pubmed/30830936 http://dx.doi.org/10.1371/journal.pone.0213283 |