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Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells

Accumulation of mutations in mitochondrial DNA (mtDNA) is thought to be responsible for mitochondrial, and other, diseases and biological phenomena, such as diabetes, cancer, neurodegenerative diseases, and aging. Mouse models may elucidate the relationship between mutations in mtDNA and these abnor...

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Detalles Bibliográficos
Autores principales:	Ishikawa, Kaori, Kobayashi, Kohei, Yamada, Akihito, Umehara, Moe, Oka, Toshihiko, Nakada, Kazuto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398856/ https://www.ncbi.nlm.nih.gov/pubmed/30830936 http://dx.doi.org/10.1371/journal.pone.0213283

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