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Kaposi’s sarcoma-associated herpesvirus ORF57 protein protects viral transcripts from specific nuclear RNA decay pathways by preventing hMTR4 recruitment

Nuclear RNAs are subject to a number of RNA decay pathways that serve quality control and regulatory functions. As a result, any virus that expresses its genes in the nucleus must have evolved mechanisms that avoid these pathways, but the how viruses evade nuclear RNA decay remains largely unknown....

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Detalles Bibliográficos
Autores principales: Ruiz, Julio C., Hunter, Olga V., Conrad, Nicholas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398867/
https://www.ncbi.nlm.nih.gov/pubmed/30785952
http://dx.doi.org/10.1371/journal.ppat.1007596