Shortcuts to intestinal carcinogenesis by genetic engineering in organoids

Inactivation of the Adenomatous polyposis coli (APC) gene is an initiating and the most relevant event in most sporadic cases of colorectal cancer, providing a rationale for using Apc‐mutant mice as the disease model. Whereas carcinogenesis has been observed only at the organism level, the recent de...

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Detalles Bibliográficos
Autores principales: Maru, Yoshiaki, Onuma, Kunishige, Ochiai, Masako, Imai, Toshio, Hippo, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398887/
https://www.ncbi.nlm.nih.gov/pubmed/30637899
http://dx.doi.org/10.1111/cas.13938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398887/
https://www.ncbi.nlm.nih.gov/pubmed/30637899
http://dx.doi.org/10.1111/cas.13938

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