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Epithelial‐mesenchymal transition via transforming growth factor beta in pancreatic cancer is potentiated by the inflammatory glycoprotein leucine‐rich alpha‐2 glycoprotein
We previously showed that an inflammation‐related, molecule leucine‐rich alpha‐2 glycoprotein (LRG) enhances the transforming growth factor (TGF)‐β1‐induced phosphorylation of Smad proteins and is elevated in patients with pancreatic ductal adenocarcinoma (PDAC). As TGF‐β/Smad signaling is considere...
Autores principales: | Otsuru, Toru, Kobayashi, Shogo, Wada, Hiroshi, Takahashi, Tsuyoshi, Gotoh, Kunihito, Iwagami, Yoshifumi, Yamada, Daisaku, Noda, Takehiro, Asaoka, Tadafumi, Serada, Satoshi, Fujimoto, Minoru, Eguchi, Hidetoshi, Mori, Masaki, Doki, Yuichiro, Naka, Testuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398893/ https://www.ncbi.nlm.nih.gov/pubmed/30575211 http://dx.doi.org/10.1111/cas.13918 |
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