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Platforms of in vivo genome editing with inducible Cas9 for advanced cancer modeling

The emergence of clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 technology has dramatically advanced how we manipulate the genome. Regarding in vivo experiments, Cas9‐transgenic animals could provide efficient and complex genome editing. However, this potential has not been f...

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Detalles Bibliográficos
Autores principales: Jo, Norihide, Sogabe, Yuko, Yamada, Yosuke, Ukai, Tomoyo, Kagawa, Harunobu, Mitsunaga, Kanae, Woltjen, Knut, Yamada, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398895/
https://www.ncbi.nlm.nih.gov/pubmed/30588718
http://dx.doi.org/10.1111/cas.13924