Cargando…

Platforms of in vivo genome editing with inducible Cas9 for advanced cancer modeling

The emergence of clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 technology has dramatically advanced how we manipulate the genome. Regarding in vivo experiments, Cas9‐transgenic animals could provide efficient and complex genome editing. However, this potential has not been f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jo, Norihide, Sogabe, Yuko, Yamada, Yosuke, Ukai, Tomoyo, Kagawa, Harunobu, Mitsunaga, Kanae, Woltjen, Knut, Yamada, Yasuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398895/ https://www.ncbi.nlm.nih.gov/pubmed/30588718 http://dx.doi.org/10.1111/cas.13924

Ejemplares similares

In vivo reprogramming drives Kras-induced cancer development
por: Shibata, Hirofumi, et al.
Publicado: (2018)

N-Terminal Amino Acids Determine KLF4 Protein Stability in 2A Peptide-Linked Polycistronic Reprogramming Constructs
por: Reinhardt, Anika, et al.
Publicado: (2020)

DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency
por: Taguchi, Jumpei, et al.
Publicado: (2021)

Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs
por: Ikeda, Takashi, et al.
Publicado: (2018)

Microhomology-assisted scarless genome editing in human iPSCs
por: Kim, Shin-Il, et al.
Publicado: (2018)

Cell-type-specific genome editing with a microRNA-responsive CRISPR–Cas9 switch
por: Hirosawa, Moe, et al.
Publicado: (2017)

NmeCas9 is an intrinsically high-fidelity genome-editing platform
por: Amrani, Nadia, et al.
Publicado: (2018)

Unveiling epigenetic regulation in cancer, aging, and rejuvenation with in vivo reprogramming technology
por: Sogabe, Yuko, et al.
Publicado: (2018)

Orthogonal Cas9–Cas9 chimeras provide a versatile platform for genome editing
por: Bolukbasi, Mehmet Fatih, et al.
Publicado: (2018)

De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency
por: Yagi, Masaki, et al.
Publicado: (2019)

Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas
por: Komura, Shingo, et al.
Publicado: (2019)

Inducible in vivo genome editing with CRISPR/Cas9
por: Dow, Lukas E, et al.
Publicado: (2015)

Publisher Correction: Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing
por: Bolukbasi, Mehmet Fatih, et al.
Publicado: (2018)

OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates
por: Kagawa, Harunobu, et al.
Publicado: (2019)

In vivo genome editing using Staphylococcus aureus Cas9
por: Ran, F. Ann, et al.
Publicado: (2015)

CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo
por: Monteys, Alex Mas, et al.
Publicado: (2017)

CRISPR/dCas9 platforms in plants: strategies and applications beyond genome editing
por: Moradpour, Mahdi, et al.
Publicado: (2019)

A Versatile and Efficient Plant Protoplast Platform for Genome Editing by Cas9 RNPs
por: Jiang, Wenzhi, et al.
Publicado: (2021)

Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation
por: Maurissen, Thomas L., et al.
Publicado: (2020)

Efficient Mitochondrial Genome Editing by CRISPR/Cas9
por: Jo, Areum, et al.
Publicado: (2015)

Efficient In Vivo Liver-Directed Gene Editing Using CRISPR/Cas9
por: Singh, Kshitiz, et al.
Publicado: (2018)

Spatial control of in vivo CRISPR–Cas9 genome editing via nanomagnets
por: Zhu, Haibao, et al.
Publicado: (2018)

Applying switchable Cas9 variants to in vivo gene editing for therapeutic applications
por: Mills, Emily M., et al.
Publicado: (2019)

Restoration of RPGR expression in vivo using CRISPR/Cas9 gene editing
por: Gumerson, Jessica D., et al.
Publicado: (2021)

Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing
por: Haldeman, Jonathan M, et al.
Publicado: (2019)

Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System
por: Meneghini, Vasco, et al.
Publicado: (2021)

Strategies in the delivery of Cas9 ribonucleoprotein for CRISPR/Cas9 genome editing
por: Zhang, Song, et al.
Publicado: (2021)

CRISPR-Cas9 DNA Base-Editing and Prime-Editing
por: Kantor, Ariel, et al.
Publicado: (2020)

Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing
por: Wang, Kepin, et al.
Publicado: (2017)

Development of a CRISPR/Cas9 System for Methylococcus capsulatus In Vivo Gene Editing
por: Tapscott, Timothy, et al.
Publicado: (2019)

Mitigating off-target effects in CRISPR/Cas9-mediated in vivo gene editing
por: Han, Hua Alexander, et al.
Publicado: (2020)

Characterization of Brevibacillus laterosporus Cas9 (BlatCas9) for Mammalian Genome Editing
por: Gao, Ning, et al.
Publicado: (2020)

CRISPR/Cas9 or prime editing? – It depends on…
por: Schenke, Dirk
Publicado: (2020)

The causal relationship between epigenetic abnormality and cancer development: in vivo reprogramming and its future application
por: YAMADA, Yosuke, et al.
Publicado: (2018)

Expanding CRISPR/Cas9 Genome Editing Capacity in Zebrafish Using SaCas9
por: Feng, Yan, et al.
Publicado: (2016)

FrCas9 is a CRISPR/Cas9 system with high editing efficiency and fidelity
por: Cui, Zifeng, et al.
Publicado: (2022)

Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia
por: Pankowicz, Francis P., et al.
Publicado: (2016)

In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
por: Kim, Eunji, et al.
Publicado: (2017)

A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing
por: Chen, Guojun, et al.
Publicado: (2019)

CRISPR/Cas9 Genome Editing for Tissue‐Specific In Vivo Targeting: Nanomaterials and Translational Perspective
por: Sahel, Deepak Kumar, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_p2m8juk3kqq1hfae8bfq5lb3ap