p53/Lactate dehydrogenase A axis negatively regulates aerobic glycolysis and tumor progression in breast cancer expressing wild‐type p53

Tumor suppressor p53 is a master regulator of apoptosis and plays key roles in cell cycle checkpoints. p53 responds to metabolic changes and alters metabolism through several mechanisms in cancer. Lactate dehydrogenase A (LDHA), a key enzyme in glycolysis, is highly expressed in a variety of tumors...

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Detalles Bibliográficos
Autores principales: Zhou, Yao, Niu, Weihong, Luo, Yanwei, Li, Hui, Xie, Yong, Wang, Heran, Liu, Yukun, Fan, Songqing, Li, Zheng, Xiong, Wei, Li, Xiaoling, Ren, Caiping, Tan, Ming, Li, Guiyuan, Zhou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398928/
https://www.ncbi.nlm.nih.gov/pubmed/30618169
http://dx.doi.org/10.1111/cas.13928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398928/
https://www.ncbi.nlm.nih.gov/pubmed/30618169
http://dx.doi.org/10.1111/cas.13928

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