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A Y-chromosome shredding gene drive for controlling pest vertebrate populations

Self-replicating gene drives that modify sex ratios or infer a fitness cost could be used to control populations of invasive alien species. The targeted deletion of Y sex chromosomes using CRISPR technology offers a new approach for sex bias that could be incorporated within gene-drive designs. We i...

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Detalles Bibliográficos
Autores principales: Prowse, Thomas AA, Adikusuma, Fatwa, Cassey, Phillip, Thomas, Paul, Ross, Joshua V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398975/
https://www.ncbi.nlm.nih.gov/pubmed/30767891
http://dx.doi.org/10.7554/eLife.41873