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Division of labour between PP2A-B56 isoforms at the centromere and kinetochore

PP2A-B56 is a serine/threonine phosphatase complex that regulates several major mitotic processes, including sister chromatid cohesion, kinetochore-microtubule attachment and the spindle assembly checkpoint. We show here that these key functions are divided between different B56 isoforms that locali...

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Detalles Bibliográficos
Autores principales: Vallardi, Giulia, Allan, Lindsey A, Crozier, Lisa, Saurin, Adrian T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398977/
https://www.ncbi.nlm.nih.gov/pubmed/30829571
http://dx.doi.org/10.7554/eLife.42619