MYOD1 functions as a clock amplifier as well as a critical co-factor for downstream circadian gene expression in muscle

In the present study we show that the master myogenic regulatory factor, MYOD1, is a positive modulator of molecular clock amplitude and functions with the core clock factors for expression of clock-controlled genes in skeletal muscle. We demonstrate that MYOD1 directly regulates the expression and...

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Detalles Bibliográficos
Autores principales: Hodge, Brian A, Zhang, Xiping, Gutierrez-Monreal, Miguel A, Cao, Yi, Hammers, David W, Yao, Zizhen, Wolff, Christopher A, Du, Ping, Kemler, Denise, Judge, Andrew R, Esser, Karyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398978/
https://www.ncbi.nlm.nih.gov/pubmed/30789342
http://dx.doi.org/10.7554/eLife.43017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398978/
https://www.ncbi.nlm.nih.gov/pubmed/30789342
http://dx.doi.org/10.7554/eLife.43017

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