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Programmed conversion of hypertrophic chondrocytes into osteoblasts and marrow adipocytes within zebrafish bones

Much of the vertebrate skeleton develops from cartilage templates that are progressively remodeled into bone. Lineage tracing studies in mouse suggest that chondrocytes within these templates persist and become osteoblasts, yet the underlying mechanisms of this process and whether chondrocytes can g...

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Detalles Bibliográficos
Autores principales: Giovannone, Dion, Paul, Sandeep, Schindler, Simone, Arata, Claire, Farmer, D'Juan T, Patel, Punam, Smeeton, Joanna, Crump, J Gage
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398980/
https://www.ncbi.nlm.nih.gov/pubmed/30785394
http://dx.doi.org/10.7554/eLife.42736