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Microtubule plus-ends act as physical signaling hubs to activate RhoA during cytokinesis

Microtubules (MTs) are essential for cleavage furrow positioning during cytokinesis, but the mechanisms by which MT-derived signals spatially define regions of cortical contractility are unresolved. In this study cytokinesis regulators visualized in Drosophila melanogaster (Dm) cells were found to l...

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Detalles Bibliográficos
Autores principales: Verma, Vikash, Maresca, Thomas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398982/
https://www.ncbi.nlm.nih.gov/pubmed/30758285
http://dx.doi.org/10.7554/eLife.38968