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Rapid changes in morphogen concentration control self-organized patterning in human embryonic stem cells
During embryonic development, diffusible signaling molecules called morphogens are thought to determine cell fates in a concentration-dependent way. Yet, in mammalian embryos, concentrations change rapidly compared to the time for making cell fate decisions. Here, we use human embryonic stem cells (...
Autores principales: | Heemskerk, Idse, Burt, Kari, Miller, Matthew, Chhabra, Sapna, Guerra, M Cecilia, Liu, Lizhong, Warmflash, Aryeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398983/ https://www.ncbi.nlm.nih.gov/pubmed/30829572 http://dx.doi.org/10.7554/eLife.40526 |
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