Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes

Autophagy is the major mechanism involved in degradation and recycling of intracellular components, and its alterations have been proposed to cause beta cell dysfunction. In this study, we explored the effects of autophagy modulation in human islets under conditions associated to endoplasmic reticul...

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Detalles Bibliográficos
Autores principales: Bugliani, M., Mossuto, S., Grano, F., Suleiman, M., Marselli, L., Boggi, U., De Simone, P., Eizirik, D. L., Cnop, M., Marchetti, P., De Tata, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399112/
https://www.ncbi.nlm.nih.gov/pubmed/30863363
http://dx.doi.org/10.3389/fendo.2019.00052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399112/
https://www.ncbi.nlm.nih.gov/pubmed/30863363
http://dx.doi.org/10.3389/fendo.2019.00052

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