Activation of Nicotinic Acetylcholine α7 Receptor Attenuates Progression of Monocrotaline-Induced Pulmonary Hypertension in Rats by Downregulating the NLRP3 Inflammasome

Background: Inflammation and altered immunity contribute to the development of pulmonary arterial hypertension (PH). The alpha 7 nicotinic acetylcholine receptor (α7nAChR) possesses anti-inflammatory activities. The current study was performed to investigate the effects of a selective α7nAChR agonis...

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Detalles Bibliográficos
Autores principales: Deng, Yan, Guo, Sheng-Lan, Wei, Bin, Gao, Xing-Cui, Zhou, Ying-Chuan, Li, Jia-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399137/
https://www.ncbi.nlm.nih.gov/pubmed/30863307
http://dx.doi.org/10.3389/fphar.2019.00128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399137/
https://www.ncbi.nlm.nih.gov/pubmed/30863307
http://dx.doi.org/10.3389/fphar.2019.00128

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